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DNA Repair |
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genomic instability, epigenetic effects |
Canela, A., Martín-Caballero, J., Flores, J.M., and Blasco, M.A. (2004). Constitutive expression of Tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. Mol Cell Biol 24, 4275-4293
Espejel, S., Klatt, P., Martín-Caballero, J.M., J., Flores, and Blasco, M.A. (2004). Shorter telomeres, accelerated aging and increased lymphoma in DNA-PKcs-deficient mice. EMBO Reports 5, 503-509
Sabatier L., Ricoul M., Pottier G., and Murnane JP. The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line Mol Cancer Res. 2005 Mar;3(3):139-50
Surralles J, Jackson SP., Jasin M, Kastan MB.,. West SC, Joenje H (2004) Molecular cross talk among chromosome fragility syndromes. Genes and Development Jun 15;18(12):1359-70. |
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mechanisms of tumorigenesis |
Ellender M, Harrison JD, Edwards AA, Bouffler SD and Cox R Direct single gene mutational events account for radiation-induced intestinal adenoma yields in Apc(Min/+) mice. Radiation Research 2005 May;163(5):552-6 |
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genetic susceptibility to radiogenic tumours |
Atkinson MJ Intracellular Sequestration of 223Ra by the Iron-storage Protein Ferritin Radiation Research |
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modelling |
Ballarini F. and Ottolenghi A. A model of chromosome aberration induction and Chronic Myeloid Leukaemia incidence at low doses Radiation and Environmental Biophysics 2004 Sep;43(3):165-71
Bijwaard H and Brugmans M Multistage cancer models of bone cancer induction in beagles and mice by radium and plutonium compared to Humans Proceedings HEIR 2004 conference
Fakir H., Hofmann W., Caswell R.S., Laniece-Aubineau I. Microdosimetry of inhomogeneous radon progeny distributions in bronchial airways Radiation Protection Dosimetry 2005;113(2):129-39
Friedland W, Dingfelder M, Jacob P, Paretzke H G. Calculated DNA double-strand break and fragmentation Radiation Physics and Chemistry 72 (2005) 279–286
Heidenreich W.F., Mueller W.A., Paretzke H.G., and Rosemann M. A two-stage clonal expansion model for bone cancer risk in mice exposed to 224Ra: protraction effects from promotion. Radiat Environ Biophys. 2005 May;44(1):61-7
Little M.P., Filipe J.A.N., Prise K.M., Folkard M., Belyakov O.V. A model for radiation-induced bystander effects, with allowance for spatial position and the effects of cell turnover J Theor Biol 2005 232 329-38 |
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list of 161 publications |
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selected publications
